Hypoglycemia
Hypoglycemia, or low blood sugar, is a serious condition that
can occur in young puppies, especially toy breeds.  Early
recognition and proper treatment is the key to preventing
potentially serious health consequences. If a puppy is bright
and bouncy one minute, but is down, depressed and
disoriented the next, it could be a sigh of hypoglycemia. The
maintenance of proper blood sugar levels is vital, as the
puppy's brain is entirely dependant on blood sugar as a
source of energy. Thus, sighs of low blood sugar are usually
related to nervous system dysfunction.

Clinical signs of hypoglycemia can vary according to how
rapidly the blood glucose falls below normal.  A rapid fall
results in Dilated (enlarged) pupils, increased heart rate,
nervousness, tremors, vocalizing and irritability. A gradual
fall in blood glucose can result in visual disturbances
(apparent blindness) mental dullness, confusion, seizures,
decreased heart rate and coma.  Both scenarios can also
result in dehydration and hypothermia (decreased body
temperature.
The Cause
This condition is typically caused by a puppy being unable
to adapt to less frequent feeding during the post-weaning
period. Young puppies must receive nutrition every few hours.  
Puppies typically have very few fat reserves to provide energy
in a crisis. If nutrition is not provided on a frequent  
schedule, body glucose stores may become depleted. If this
occurs, a puppy's immature liver bay be unable to
produce/process glucose quickly enough to meet the body's
needs.
Prevention
In order to prevent or limit hypoglycemia, be sure that the
puppy has food available at all times and you monitor for
adequate consumption.  Also be aware that many factors can
contribute to a puppy not eating as it should.  These include
any type of stress, such as infection, vaccinations, excess
physical exertion (playing very hard)  weaning, poor
nutrition, hypothermia, gastric upset, etc.
Treatment
Since hypoglycemia, dehydration, and hypothermia often all
occur together,  all three conditions must be corrected.
Treatment should begin by contacting your veterinarian.
Maintaining a warm, humid environment (85 degreed, 85
percent humidity) is very important. The body temperature
should be raised and maintained above 95 degrees (hot water
bottles, heating pad wrapped in a towel, hair dryer, etc.) A
veterinarian may advise oral sugar supplementation
(dextrose syrup, honey, sugar water or nutri-cal)  if the
puppy can swallow typically one cc or ml per pound of body
weight every hour. As the condition improves, moist food and
water should then be offered (forced is necessary) while
slowly weaning the pup off the sugar supplementation.  The
veterinarian may start an intravenous line or subcutaneous
fluids if the condition warrants it. Frequent
high-carbohydrate feeding are necessary to prevent
recurrence. The condition usually resolves in a short period
of time with steady food intake, stress reduction and
maturity. If you think your puppy may be suffering from
hypoglycemia, be sure to reach out to a veterinarian
immediately. Follow his/her advice and, in most cases,
treatment of this condition will be 100 percent successful.

No  puppies or dogs on the website will be guaranteed against
Hypoglycemia, it is the responsibility of the new owner to
make sure the puppy or dog is eating properly !